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Claudin-18.2

Claudin-18.2信息

英文名称:Claudin-18 splice variant 2上市药物数量1
中文名称密蛋白-18剪接变体2临床药物数量74
靶点别称UNQ778/PRO1572，CLDN18，Claudin 18，Surfactant Associated Protein J，Surfactant， Pulmonary Associated Protein J，Surfactant Associated 5，Claudin-18，SFTA5，SFTPJ，Claudin 18.2，CLDN18.2最高研发阶段临床三期
英文名称:Claudin-18 splice variant 2
中文名称密蛋白-18剪接变体2
靶点别称UNQ778/PRO1572，CLDN18，Claudin 18，Surfactant Associated Protein J，Surfactant， Pulmonary Associated Protein J，Surfactant Associated 5，Claudin-18，SFTA5，SFTPJ，Claudin 18.2，CLDN18.2
上市药物数量1
临床药物数量74
最高研发阶段Phase 3 Clinical

Claudin-18.2产品列表

  • 属性

    Cell (1)Protein (8)Antibody (1)Kits (1)

  • 产品库

    在线 (15)

  • 物种

    Human (5)Human / Cynomolgus (2)Mouse (4)

  • 标签

    - (11)His Tag & Strep Tag (3)GFP Tag (1)

  • 标记

    (1)Unconjugated (7)GFP Fusion (1)Biotin-labeled (2)

共 11 项数据
  • 1
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Claudin-18.2分子背景

Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on short-lived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells.

Claudin-18.2分子别名

Claudin-18.2,CLDN18,Claudin-18

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产品评论

  • 19********qq.com 2024-05-23
    0人点赞
    Mouse Claudin-18.2 Protein, His,Twin-Strep Tag (Detergent)
    来自于小鼠的抗原，在种属特异性实验中取得了很好的效果，有很高的质量，使用方法及保存方法都很简化，发货快，支持acro
  • 19********qq.com 2024-05-23
    0人点赞
    Fluorescent Human Claudin-18.2 Full Length Protein (VLP)
    用于检测治疗胃癌药物的结合活性，展现出良好的亲和能力，与之前使用的其他国产Claudin18.2对比，性价比更高。
  • ba*******126.com 2023-08-01
    6人点赞
    Human Claudin-18.2 Full Length Protein (VLP)
    此款产品使用起来效果非常可靠，使用方法简洁，效果稳定可靠，结果重现良好，而且产品储存起来非常稳定，在放置了一年后依然可以使用，实验结果挺好的，还会继续购买该产品的！
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