HLA-A*0201 & B2M & Vaccinia virus (IMYDIINSV)分子背景
Among the nonvirion proteins of the vaccinia virus (VACV), a 94-kDa long protein is most abundantly present; the protein is a truncated form of the 150-kDa A-type inclusion (ATI) protein of the cowpox virus encoded by the ati gene. This VACV protein does not form intracellular ATIs, being as it is a major immunogen upon infection/immunization of humans or animals with the VACV. variants demonstrated that the mutant LIVPΔati elicits a stronger protective response compared to the parent LIVP. The human HLA-A*0201 Vaccinia virus IMYDIINSV complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and IMYDIINSV peptide of the vaccinia virus.