HLA-A*1101 & B2M & EGF R (KITDFGRAK)分子背景
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. The Human HLA-A*1101 & B2M & EGF R (KITDFGRAK) protein is a complex of HLA-A*1101 of the MHC Class I, B2M, and KITDFGRAK peptide of the EGF R.