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 >  Protein>UBE1 >UB1-H5248

Human UBE1 / UBA1 Protein, His Tag

分子别名(Synonym)

A1S9T and BN75 temperature sensitivity complementing,A1S9T,A1ST,AMCX1,GXP1,MGC4781,POC20 centriolar protein homolog,POC20,Protein A1S9,SMAX2,UBA1,UBA1, ubiquitin-activating enzyme E1 homolog A,UBA1A,UBE1,UBE1A1S9,UBE1X,ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivitycomplementing),Ubiquitin-activating enzyme E1,Ubiquitinactivating Enzyme,Ubiquitin-activating Enzyme,ubiquitin-like modifier activating enzyme 1,ubiquitin-like modifier-activating enzyme 1

表达区间及表达系统(Source)

Human UBE1/UBA1, His Tag (UB1-H5248) is expressed from Baculovirus-Insect cells. It contains AA Ser 2- Arg 1058 (Accession # P22314-1).

Request for sequence

蛋白结构(Molecular Characterization)

UBE1 Structure

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 119.8 kDa. The protein migrates as 80-110 kDa under reducing (R) condition (SDS-PAGE).

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Supplied as 0.2 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

运输(Shipping)

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储(Storage)

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. The product MUST be stored at -70°C or lower upon receipt;
  2. -70°C for 3 months under sterile conditions.
 

电泳(SDS-PAGE)

UBE1 SDS-PAGE

Human UBE1/UBA1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

 

背景(Background)

The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]

 

前沿进展

 
 
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UBE1靶点信息
英文全称:Ubiquitin-like modifier-activating enzyme 1
中文全称:泛素样修饰物活化酶-1
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:1详情
最高研发阶段:临床一期
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