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 >  Protein>Transferrin R2 alpha >TRA-H5263

Human Transferrin R2 alpha Protein, Fc Tag

分子别名(Synonym)

TfR2

表达区间及表达系统(Source)

Human Transferrin R2 alpha, Fc Tag (TRA-H5263) is expressed from human 293 cells (HEK293). It contains AA Gly 112 - Phe 801 (Accession # Q9UP52-1).

Predicted N-terminus: Pro

Request for sequence

蛋白结构(Molecular Characterization)

Transferrin R2 alpha Structure

This protein carries a human IgG1 Fc tag at the N-terminus

The protein has a calculated MW of 102.8 kDa. The protein migrates as 105-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 0.2 M Arginine with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Transferrin R2 alpha SDS-PAGE

Human Transferrin R2 alpha, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

 

背景(Background)

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

 

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