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 >  Protein>CXCL3 >CX3-H5263

Human CXCL3 Protein, Fc Tag (MALS verified)

分子别名(Synonym)

CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3

表达区间及表达系统(Source)

Human CXCL3 Protein, Fc Tag (CX3-H5263) is expressed from human 293 cells (HEK293). It contains AA Ala 35 - Asn 107 (Accession # P19876).

Predicted N-terminus: Pro

Request for sequence

蛋白结构(Molecular Characterization)

CXCL3 Structure

This protein carries a human IgG1 Fc tag at the N-terminus

The protein has a calculated MW of 34 kDa. The protein migrates as 38-41 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>90% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

CXCL3 SDS-PAGE

Human CXCL3 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS

CXCL3 SEC-MALS

The purity of Human CXCL3 Protein, Fc Tag (Cat. No. CX3-H5263) is more than 90% and the molecular weight of this protein is around 65-85 kDa verified by SEC-MALS.

Report

 

背景(Background)

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils.

 

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