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 >  Protein>CCL11 >CC1-H51H3

Human CCL11 Protein, His Tag

分子别名(Synonym)

SCYA11

表达区间及表达系统(Source)

Human CCL11 Protein, His Tag (CC1-H51H3) is expressed from E. coli cells. It contains AA Gly 24 - Pro 97 (Accession # P51671).

Predicted N-terminus: Met

Request for sequence

蛋白结构(Molecular Characterization)

CCL11 Structure

This protein carries a polyhistidine tag at the N-terminus

The protein has a calculated MW of 10.1 kDa. The protein migrates as 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>90% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, 250mM NaCl, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

CCL11 SDS-PAGE

Human CCL11 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

 

背景(Background)

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

 

前沿进展

 
 
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CCL11靶点信息
英文全称:Eotaxin
中文全称:嗜酸细胞活化趋化因子
种类:
上市药物数量:0详情
临床药物数量:0详情
最高研发阶段:临床前
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