描述/背景(Background)
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
种属(Host Species)
Rabbit
克隆号(Clone)
2D8
适用方法(Application)
IHC
效价(Property)
1:1000
状态(State)
Liquid
阳性对照(Positive Control)
Human Tonsil Tissues
克隆类型(Clonality)
Monoclonal
分子别名(Synonym)
DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1
研究领域(Research Field)
Cancer Drug Targets
抗体来源(Source)
Rabbit
同种型(Isotype)
IgG
储存(Storage)
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
典型数据(Typical Data)
质控样本(Control Sample)
Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S262 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
肿瘤样本(Cancer Sample)
Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S262 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.