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 >  Antibody>CD45 (LCA) >HGS-S261

Recombinant Monoclonal Anti-CD45(LCA) Antibody, Rabbit (1C3)

描述/背景(Background)

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).

种属(Host Species)

Rabbit

克隆号(Clone)

1C3

适用方法(Application)

IHC

效价(Property)

1:1000

状态(State)

Liquid

阳性对照(Positive Control)

Human Tonsil Tissues

克隆类型(Clonality)

Monoclonal

分子别名(Synonym)

PTPRC, CD45, GP180, LCA, T200

研究领域(Research Field)

Cancer Drug Targets

抗体来源(Source)

Rabbit

同种型(Isotype)

IgG

储存(Storage)

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

 

典型数据(Typical Data)

质控样本(Control Sample)

CD45 (LCA) CONTROL SAMPLE

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S261 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

肿瘤样本(Cancer Sample)

CD45 (LCA) CANCER SAMPLE

CD45 (LCA) CANCER SAMPLE

CD45 (LCA) CANCER SAMPLE

CD45 (LCA) CANCER SAMPLE

Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S261 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

 

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