膜杰作
Star Staining
& Cat.No. | Items | Size （2mg） | Size（2mg X 5） |
| Particle size | 2 μm | 2 μm |
| Physical appearance | Powder mixture | Powder mixture |
| Amount of Coupled Protein | ≈1371pmol(48μg) uPAR protein/mg beads | ≈1371pmol(48μg) uPAR protein/mg beads |
| Capacity | >277pmol (20μg) Anti-uPAR Ab/mg beads | >277pmol (20μg) Anti-uPAR Ab/mg beads |
| Formulation | PBS, pH7.4,with 10% Trehalose | PBS, pH7.4,with 10% Trehalose |
| Reconstitution | 2mL ultrapure water (1 mg beads/mL) | 2mL ultrapure water (1 mg beads/mL) |
背景（Background）
Tumors are the result of uncontrolled proliferation of cells in different organs. Tumor development is a multistage process, that includes the generation of primary tumors, separation of tumors from primary sites, degradation of extracellular matrix (ECM), and distant metastasis of tumors. A variety of genes play important roles in the development of tumors, including the cell surface receptor urokinase-type plasminogen activator receptor (uPAR). uPAR is highly expressed in a variety of tumor cells, and a variety of signals regulated by uPAR play significant roles in tumor cell proliferation and metastasis, tumor-related glycolysis, the tumor microenvironment and angiogenesis. Studies have found that some specific drugs and antibodies have unique inhibitory effects on uPAR.
应用说明（Application）
This product is intended for immunocapture, biopanning and flow cytometry. This is a non-sterile product.
重构方法（Reconstitution）
See Certificate of Analysis (CoA) for detailed instruction.
存储（Storage）
Upon receipt, please store the Beads at -20°C. The shelf life is 1 year at -20 °C.
Please avoid more than 3 freeze-thaw cycles once reconstitution, immediate use after reconstitution is highly recommended.
制剂（Formulation）
Please contact us for detailed information.
Contact us for customized product form or formulation.
典型数据-Typical Data
Immobilized 48.8μg Biotinylated Human uPAR protein to 1mg Beads can bind the Anti-uPAR Antibody with an EC50 0.52 μg/mL (QC tested).
Protocol
