膜杰作
Star Staining
& Cat.No. | Items | Size （2mg） | Size（2mg X 5） |
| Particle size | 2 μm | 2 μm |
| Physical appearance | Powder mixture | Powder mixture |
| Amount of Coupled Protein | ≈332.9 pmol (31μg) FAP protein/mg beads | ≈332.9 pmol (31μg) FAP protein/mg beads |
| Capacity | >133.3 pmol (20μg) Anti-FAP Ab/mg beads | >133.3 pmol (20μg) Anti-FAP Ab/mg beads |
| Formulation | PBS, pH7.4,with 10% Trehalose | PBS, pH7.4,with 10% Trehalose |
| Reconstitution | 2mL ultrapure water (1 mg beads/mL) | 2mL ultrapure water (1 mg beads/mL) |
背景（Background）
FAP (also known as seprase) is a Type II transmembrane serine protease. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences. Degrade also gelatin, heat-denatured type I collagen. Also has dipeptidyl peptidase activity, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. The plasma membrane form, in association with either DPP4, PLAUR or integrins, is involved in the pericellular proteolysis of the extracellular matrix (ECM), and hence promotes cell adhesion, migration and invasion through the ECM. Promotes glioma cell invasion through the brain parenchyma by degrading the proteoglycan brevican. Acts as a tumor suppressor in melanocytic cells through regulation of cell proliferation and survival in a serine protease activity-independent manner.
应用说明（Application）
This product is intended for immunocapture, biopanning. This is a non-sterile product.
重构方法（Reconstitution）
See Certificate of Analysis (CoA) for detailed instruction.
存储（Storage）
Upon receipt, please store the Beads at -20°C. The shelf life is 1 year at -20 °C. Once reconstitution, please aliquote and store under -70°C for no more than 3 months, and avoid repeated freeze-thaw cycles. Immediate use after reconstitution is highly recommended.
Please avoid more than 3 freeze-thaw cycles once reconstitution, immediate use after reconstitution is highly recommended.
制剂（Formulation）
Please contact us for detailed information.
Contact us for customized product form or formulation.
典型数据-Typical Data
Immobilized 33.8μg Biotinylated Human FAP protein to 1mg Beads can bind the Anti-FAP Antibody with an EC50 0.13 μg/mL (QC tested).
Protocol
