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Polyclonal GFAP Antibody, Rabbit IgG

抗体来源(Source)

Polyclonal GFAP Antibody, Rabbit IgG is a polyclonal antibody purified from rabbit serum.
Gene Synonyms: glial fibrillary acidic protein.

种属(Species)

Rabbit

亚型(Isotype)

Rabbit IgG

抗体类型(Antibody Type)

Polyclonal Antibody

种属反应性(Reactivity)

Mouse, Rat, Human, Other species have not been tested.

免疫原(Immunogen)

Mouse GFAP fragment fused to GST.

特异性(Specificity)

This product is a specific antibody specifically reacts with GFAP.

应用(Application)

ApplicationRecommended Usage
IF1:200~500

纯化(Purification)

Protein A purified/ Protein G purified

制剂(Formulation)

Supplied as 0.2 μm filtered solution in pH7.4, PBS, 50 mM Tris, 50 Mm Glycine with 40% glycerol as protectant.

Contact us for customized product form or formulation.

运输(Shipping)

This product is supplied and shipped with blue ice, please inquire the shipping cost.

存储(Storage)

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. Shipped at -20°C. Store at -20 for 3 years and -80°C for 5 years. Avoid freeze/thaw cycle.
 

活性(Bioactivity)-Immunostaining

GFAP IMMUNOSTAINING

2D cell staining: Immunofluorescent staining (10X) of cerebral organoid-derived neurons (CIPO-BWL001K) labeling GFAP (Red) with purified GFP-S453 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.

Protocol

GFAP IMMUNOSTAINING

3D organoid staining: Immunofluorescent staining (10X) of cerebral organoid (CIPO-BWL001K) labeling GFAP (Green) with purified GFP-S453 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.

Protocol

 

背景(Background)

The glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature astrocytes, but also an important component of the cytoskeleton in astrocytes during development. GFAP has been shown to be involved in astrocyte functions, which are important during regeneration, synaptic plasticity and reactive gliosis. It is used as a marker to distinguish astrocytes from other glial cells during development.

Middeldorp J, Hol EM. Prog Neurobiol. 2011;93(3):421-43. doi: 10.1016/j.pneurobio.2011.01.005.

General Notes: FOR RESEARCH USE ONLY.

 

前沿进展

 
 
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GFAP靶点信息
英文全称:Glial fibrillary acidic protein
中文全称:神经胶质纤维酸性蛋白
种类:Homo sapiens
上市药物数量:1详情
临床药物数量:1详情
最高研发阶段:批准上市
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