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 >  Protein>BTLA >BTA-M52E2

Mouse BTLA Protein, His Tag

分子别名(Synonym)

BTLA,CD272

表达区间及表达系统(Source)

Mouse BTLA, His Tag (BTA-M52E2) is expressed from human 293 cells (HEK293). It contains AA Glu 30 - Gly 176 (Accession # Q32MV9).

Predicted N-terminus: Glu 30

Request for sequence

蛋白结构(Molecular Characterization)

BTLA Structure

This protein carries a polyhistidine tag at the C-terminus

The protein has a calculated MW of 18.6 kDa. The protein migrates as 30-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

BTLA SDS-PAGE

Mouse BTLA, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

 

背景(Background)

B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.

 

前沿进展

 
 
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BTLA靶点信息
英文全称:B- and T-lymphocyte attenuator
中文全称:B和T淋巴细胞衰减因子
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:5详情
最高研发阶段:临床三期
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