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CLEC12A信息

英文名称:C-Type lectin domain family 12 member A
中文名称:C型凝集素结构域家族12成员A
靶点别称:CD371 Antigen,C-Type Lectin-Like Molecule 1,MICL,CD371,CLEC12A,DCAL2,DCAL-2,Dendritic cell-associated lectin 2,C-Type Lectin Domain Family 12 Member A,Myeloid Inhibitory C-Type Lectin-Like Receptor,CLL-1,CLL1,C-Type Lectin Domain Family 12, Member A,C-Type Lectin-Like Molecule-1,C-Type Lectin Protein CLL-1
上市药物数量:0
临床药物数量:21
最高研发阶段:临床三期

CLEC12A分子别名

CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371

CLEC12A分子背景

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

CLEC12A临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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