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 > 【CD209】

CD209产品列表

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CD9-H5246
Human		 Human CD209 / DC-SIGN Protein, His Tag
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CD209分子别名

DC-SIGN,CD209,DC-SIGN1,CLEC4L

CD209分子背景

CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.

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