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PADI2信息

英文名称:Protein-arginine deiminase type-2
中文名称:蛋白质精氨酸脱亚胺酶2
靶点别称:Peptidyl Arginine Deiminase 2,PDI2,KIAA0994,Peptidyl Arginine Deiminase, Type II,Protein-Arginine Deiminase Type II,EC 3.5.3.15,PAD-H19,PAD2,Peptidylarginine Deiminase II
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

PADI2分子别名

PADI2,PAD-H19,KIAA0994,PAD2,PDI2

PADI2分子背景

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.

PADI2临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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