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Carbonic Anhydrase II信息

英文名称:Carbonic anhydrase II
中文名称:碳酸酐酶II
靶点别称:Carbonic anhydrase II,Carbonic Anhydrase B,EC:4.2.1.1,Carbonate Dehydratase II,Carbonic Anhydrase C,EC 4.2.1.1,CA2,Epididymis Luminal Protein 76,Car2,HEL-76,Epididymis Secretory Protein Li 282,CA-II,CAC,CAII,HEL-S-282,Carbonic Anhydrase 2,Carbonic Dehydratase
上市药物数量:5
临床药物数量:1
最高研发阶段:批准上市

Carbonic Anhydrase II产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CA2-H5228
Human
Human Carbonic Anhydrase II / CA2 Protein, His Tag
ACRO质量管理体系
 
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Carbonic Anhydrase II 分子别名

CA2,CA-II,CAII,Car2

Carbonic Anhydrase II 分子背景

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. They are, therefore, classified as metalloenzymes. There are at least five distinct CA families (α, β, γ, δ and ε). These families have no significant amino acid sequence similarity and in most cases are thought to be an example of convergent evolution. The α-CAs are found in humans. Carbonic anhydrase II (CA2) is also known as Carbonate dehydratase II, Carbonic anhydrase C, is one of fourteen forms of human α carbonic anhydrases. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of sodium ions in the proximal tubule. Carbonic anhydrase II has been shown to interact with Band 3 and Sodium-hydrogen antiporter 1.

Carbonic Anhydrase II 前沿进展

Carbonic Anhydrase II上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

Carbonic Anhydrase II临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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