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KR2-H52H3
Human		 Human Kremen-2 protein, His Tag
KR2-H52H4
Human		 Human Kremen-2 CUB Domain Protein, His Tag
KR2-H82E8
Human		 Biotinylated Human KREMEN2 Protein, His,Avitag™
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KREMEN2分子别名

KREMEN2, Kremen-2, KRM2, Dickkopf receptor 2,Kringle domain-containing transmembrane protein 2

KREMEN2分子背景

Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer.

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