登录 | 注册    关注公众号  
微信公众号
搜索
 > 【IL-18】

IL-18信息

英文名称:Interleukin 18
中文名称:白细胞介素18
靶点别称:Interferon gamma-inducing factor,IL-18,IFN-gamma-inducing factor,IGIF,Iboctadekin,IL18,Interleukin 18,Interleukin 18 (Interferon-Gamma-Inducing Factor),Interleukin-1 Gamma,IL-1 Gamma,IL1F4,Interferon-Gamma-Inducing Factor,Interleukin-18,IL-1g
上市药物数量:0
临床药物数量:7
最高研发阶段:临床三期

IL-18产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
GMP-L18H16
Human
GMP Human IL-18 Protein
IL8-H5114
Human
Human IL-18 Protein, premium grade
IL8-M51H3
Mouse
Mouse IL-18 Protein, His Tag
ACRO质量管理体系
 
评论(0)
 

IL-18分子别名

IL-18,Interleukin-18,IL18,IL-1 gamma,IGIF,IL1F4,IL-1F4

IL-18分子背景

Interleukin-18 (IL-18) is a potent proinflammatory cytokine that induces interferon-gamma (IFN-gamma) production from Th1 cells, NK cells and activated macrophages, particularly in the presence of IL-12. IL-18 also functions in developmental regulation of T-lymphocyte helper type I cells and in Fas-mediated cytotoxicity. Suppression of IL-18 activity is being investigated for treatment of chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis. It acts by inducing heterodimerization of the two subunits of its receptor, IL-18RAlpha and IL-18RBeta shows structural similarity to IL-1.

IL-18临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

消息提示

请输入您的联系方式,再点击提交!

确定