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 > 【4-1BB Ligand】

4-1BB Ligand信息

英文名称:Tumor necrosis factor ligand superfamily member 9
中文名称:肿瘤坏死因子配体超家族成员9
靶点别称:4-1BB ligand,4-1BBL
上市药物数量:0
临床药物数量:2
最高研发阶段:临床二期

4-1BB Ligand分子别名

4-1BB Ligand,TNFSF9,CD137L

4-1BB Ligand分子背景

Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

4-1BB Ligand临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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