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SpeB产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
SPB-S5115
Streptococcus pyogenes
SpeB (40U/μl)
ACRO质量管理体系
 
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SpeB分子别名

Streptopain,Exotoxin type B,Streptococcal cysteine proteinase

SpeB分子背景

SpeB is derived from Streptococcus pyogenes. It is an important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. It also cleaves human IL1B precursor to form biologically active IL1B and can induce apoptosis in human monocytes and epithelial cells in vitro, reduces phagocytic activity in monocytic cells. Thus, it may play a role in bacterial colonization, invasion, and inhibition of wound healing.

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