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 > 【CD39L1/ENTPD2】

CD39L1/ENTPD2信息

英文名称：Ectonucleoside triphosphate diphosphohydrolase 2
中文名称：
靶点别称：EC:3.6.1.-，NTPDase 2，CD39 antigen-like 1，Ecto-ATP diphosphohydrolase 2 (Ecto-ATPDase 2; Ecto-ATPase 2)，CD39L1
上市药物数量：0
临床药物数量：1
最高研发阶段：临床一期

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货号 物种 产品描述 蛋白结构 纯度 活性
CD1-H53H3
Human		 Human CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified)
CD1-M53H3
Mouse		 Mouse CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified)
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CD39L1/ENTPD2分子别名

CD39L1, NTPDase-2

CD39L1/ENTPD2分子背景

CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells . CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. CD39L1 plays a role in regulating thrombosis and inflammation . It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation.

CD39L1/ENTPD2临床药物信息

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