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TGF-beta RI信息

英文名称:Transforming growth factor beta receptor 1
中文名称:转化生长因子β受体1
靶点别称:EC 2.7.11,TGF-beta type I receptor,Serine/threonine-protein kinase receptor R4,TGFBR1,Activin A receptor type II-like protein kinase of 53kD,Transforming Growth Factor Beta Receptor 1,Transforming Growth Factor-Beta Receptor Type I,Activin A Receptor Type II-Like Kinase, 53kDa,Activin Receptor-Like Kinase 5,TGFR-1,ALK-5,ALK5,SKR4,Mutant Transforming Growth Factor Beta Receptor I,TGF-Beta Receptor Type-1,TGF-Beta Receptor Type I,EC 2.7.11.30,ACVRLK4,LDS1A,LDS2A,AAT5,LDS1,TBRI,ESS1,MSSE,TbetaR-I,T
上市药物数量:0
临床药物数量:8
最高研发阶段:临床二期

TGF-beta RI分子别名

TGFR-1, ALK-5, TGF-beta receptor type-1, Activin receptor-like kinase 5

TGF-beta RI分子背景

TGF type I receptor also called the activin receptor-like kinase 5 (ALK5) and involved in TGF signaling. TGFβ signaling is mediated by the interaction of TGFβ ligands (TGFβ 1, 2 or 3) with cell surface receptors, the TGF type I, type II and type III receptors. Signaling is initiated by binding of TGF to the TGF type II receptor forming a ligand-receptor complex which interacts with the TGF type I receptor.

TGF-beta RI临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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