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 > 【HLA-A*02:01 & B2M & NY-ESO-1】

HLA-A*02:01 & B2M & NY-ESO-1产品列表

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HL1-H82E4
Human		 Biotinylated Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Complex Protein (Monomer, MALS verified)
HL1-H82E6
Human		 Biotinylated Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Complex Protein (Monomer, MALS verified)
HL1-H52E8
Human		 Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein (MALS & SPR verified)
HL1-H52E7
Human		 Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein (MALS verified)
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HLA-A*02:01 & B2M & NY-ESO-1分子别名

HLA-A*02:01 & B2M & NY-ESO-1

HLA-A*02:01 & B2M & NY-ESO-1分子背景

NY-ESO-1, which is also well-known as New York esophageal squamous cell carcinoma 1, is an efficient target for cancer immunotherapy. This antigen is a member of cancer-testis antigens (CTAs) and is highly expressed in various cancers, including melanoma, ovarian, cervical cancer, etc. Adoptive T cell therapy with HLA-A2 restricted NY-ESO-1 transduced CD8+ T cells has improved the clinical response rates and overall survival of treatment-refractory melanoma patients.

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