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 > 【Complement C3a】

Complement C3a信息

英文名称：Complement C3
中文名称：补体C3
靶点别称：Complement C3，Complement Component C3a，Epididymis Secretory Sperm Binding Protein Li 62p，C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1，C3bc，C3adesArg，C3，Complement Component C3b，Complement Component 3，C3a Anaphylatoxin，Prepro-C3，CPAMD1，Acylation-Stimulating Protein Cleavage Product，HEL-S-62p，AHUS5，ARMD9，ASP，C3a，C3b
上市药物数量：1
临床药物数量：13
最高研发阶段：批准上市

Complement C3a产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
COA-H5143
Human		 Human Complement C3a Protein, His Tag
COA-H82Q3
Human		 Biotinylated Human Complement C3a Protein, His,Avitag™
COA-M5243
Mouse		 Mouse Complement C3a Protein, His Tag (HPLC verified)
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Complement C3a分子别名

Complement Component C3a,Complement C3a,C3a

Complement C3a分子背景

C3 is the major complement component serum. It is mainly synthesized by macrophages and liver. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. It is cleaved into two fragments, C3a and C3b. C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Complement C3a上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

Complement C3a临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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