登录 | 注册    关注公众号  
微信公众号
搜索
 > 【TREM-1】

TREM-1信息

英文名称:Triggering receptor expressed on myeloid cells 1
中文名称:髓系细胞表达的触发受体-1
靶点别称:Triggering Receptor Expressed On Myeloid Cells 1,CD354 Antigen,Triggering Receptor Expressed on Myeloid Cells-1,TREM-1,TREM1,CD354,Triggering receptor expressed on monocytes 1
上市药物数量:0
临床药物数量:4
最高研发阶段:临床二期

TREM-1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
TR1-H5251
Human
Human TREM-1 / CD354 Protein, Fc Tag
ACRO质量管理体系
 
评论(0)
 

TREM-1分子别名

TREM1,CD354

TREM-1分子背景

Triggering receptor expressed on myeloid cells 1 (TREM1) is also known as CD antigen CD354, and is a type I transmembrane protein with a single Ig-like domain. TREM1 is highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. TREM-1 / CD354 stimulates neutrophil and monocyte-mediated inflammatory responses, and also triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. TREM1 can interacts with TYROBP / DAP12.

TREM-1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

消息提示

请输入您的联系方式,再点击提交!

确定