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CD300a信息

英文名称:CMRF35-like molecule 8
中文名称
靶点别称:CLM-8,CD300 antigen-like family member A,CMRF-35-H9 (CMRF35-H9),CMRF35-H,IRC1/IRC2,Immunoglobulin superfamily member 12 (IgSF12),Inhibitory receptor protein 60 (IRp60),NK inhibitory receptor
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

CD300a产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CDA-H52H5
Human
Human CD300a / LMIR1 Protein, His Tag (MALS verified)
ACRO质量管理体系
 
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CD300a分子别名

CD300A,CLM-8,CMRF-35-H9,CMRF35-H9,CMRF35-H,IRC1,IRC2,IgSF12,IRp60,CMRF35H,IGSF12,LMIR1

CD300a分子背景

CD300a, expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.

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