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 > 【LRP-1】

LRP-1信息

英文名称：Low density lipoprotein receptor-related protein-1
中文名称：低密度脂蛋白受体相关蛋白1
靶点别称：Apolipoprotein E Receptor，TbetaR-V/LRP-1/IGFBP-3 Receptor，Type V Tgf-Beta Receptor，CD91 Antigen，APOER，Alpha-2-Macroglobulin Receptor，IGFBP3R1，IGFBP3R，TGFBR5，IGFBP-3R，LRP1A，CD91，A2MR，Prolow-Density Lipoprotein Receptor-Related Protein 1，Low Density Lipoprotein Receptor-Related Protein 1
上市药物数量：0
临床药物数量：0
最高研发阶段：临床前

LRP-1产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
LR1-H5256
Human		 Human LRP-1 / cluster Ⅳ Protein, Fc Tag
LR1-H5254
Human		 Human LRP-1 / cluster Ⅱ Protein, Fc Tag (MALS verified)
LR1-H5255
Human		 Human LRP-1 / cluster Ⅲ Protein, Fc Tag (MALS verified)
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LRP-1分子别名

A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R, IGFBP3R1, KPA, LRP, LRP1A, TGFBR5

LRP-1分子背景

Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor. LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and cell motility, and diseases, such as neurodegenerative diseases, atherosclerosis, and cancer.

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