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Matriptase信息

英文名称:Suppressor of tumorigenicity 14 protein
中文名称
靶点别称:ST14 Transmembrane Serine Protease Matriptase,MT-SP1,SNC19,TMPRSS14,PRSS14,CAP3,HAI,Suppression Of Tumorigenicity 14 (Colon Carcinoma),Membrane-Type Serine Protease 1,Serine Protease TADG-15,Serine Protease 14,EC 3.4.21.109,Matriptase,Prostamin,TADG15,Suppression Of Tumorigenicity 14 (Colon Carcinoma, Matriptase, Epithin),Tumor Associated Differentially Expressed Gene 15 Protein,Tumor-Associated Differentially-Expressed Gene 15 Protein,Suppression Of Tumorigenicity 14,Channel–Activating Protein
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

Matriptase产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
MAE-H5143
Human
Human Matriptase / ST14 Catalytic Domain Protein, Tag Free (active enzyme)
ACRO质量管理体系
 
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Matriptase分子别名

Matriptase

Matriptase分子背景

Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing; Cleaves various synthetic substrates with Arg or Lys at the P1 position and prefers small side-chain amino acids, such as Ala and Gly, at the P2 position.

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