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CD99信息

英文名称:CD99 antigen
中文名称:CD99抗原
靶点别称:12E7,E2 antigen,Protein MIC2,T-cell surface glycoprotein E2
上市药物数量:0
临床药物数量:1
最高研发阶段:临床二期

CD99分子别名

CD99,HBA71,MIC2,MIC2X,MIC2Y,MSK5X,12E7

CD99分子背景

CD99 antigen is also known as MIC2, single-chain type-1 glycoprotein, HBA71, MIC2X, MIC2Y, MSK5X, 12E7, which belongs to the CD99 family. CD99 / MIC2 is expressed on all leukocytes but highest on thymocytes. Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 / MIC2 plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. CD99 acts at the same site as, but independently of PECAM1. There is also experimental evidence that it binds to cyclophilin A.

CD99临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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