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 > 【CD45RO】

CD45RO信息

英文名称:Leukocyte common antigen
中文名称:白细胞共同抗原
靶点别称:PTPRC,T200,CD45,Protein Tyrosine Phosphatase, Receptor Type C,CD45 Antigen,L-CA,Protein Tyrosine Phosphatase, Receptor Type, C Polypeptide,Receptor-Type Tyrosine-Protein Phosphatase C,T200 Leukocyte Common Antigen,Leukocyte Common Antigen,T200 Glycoprotein,EC 3.1.3.48,CD45R,GP180,B220,LCA,LY5,Leukocyte Common Antigens,Protein Tyrosine Phosphatase Receptor Type C,EC:3.1.3.48
上市药物数量:0
临床药物数量:3
最高研发阶段:临床三期

CD45RO产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CDO-H52H3
Human
Human CD45RO Protein, His Tag (MALS verified)
ACRO质量管理体系
 
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CD45RO分子别名

B220, CD45, CD45R, GP180, IMD105, L-CA, LCA, LY5, T200

CD45RO分子背景

CD45RO contains exon 3, 7 and 8 and lacks the RA, RB and RC exons of the CD45 gene. CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

CD45RO临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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