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 > 【Claudin-1】

Claudin-1信息

英文名称：Claudin 1
中文名称：Claudin 1
靶点别称：Claudin-1，SEMP1，ILVASC，CLD1，Senescence-Associated Epithelial Membrane Protein 1，CLDN1
上市药物数量：0
临床药物数量：3
最高研发阶段：临床二期

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货号 物种 产品描述 蛋白结构 纯度 活性
CHEK-ATP124
Human		 HEK293/Human Claudin-1 Stable Cell Line
CL1-H52P6
Human		 Human Claudin-1 Full Length Protein (VLP)
CL1-H55D8
Human		 Human Claudin-1 Protein, Flag,His Tag (Detergent)
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Claudin-1分子别名

CLD1, ILVASC, SEMP1

Claudin-1分子背景

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]

Claudin-1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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