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 > 【G4S linker】

G4S linker产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
G4S-PFMY25
Rabbit		 PE-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S-ABFYP1
Rabbit		 Alexa Fluor 647-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S-AEFYP1
Rabbit		 Alexa Fluor™ 555-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S-AFMY25
Rabbit		 APC-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S-BLM25G0
Rabbit		 Biotinylated Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016), premium grade
G4S-CFM25G0
Rabbit		 PE-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016), premium grade
G4S-FAFYP1
Rabbit		 FITC-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S-HFM25G0
Rabbit		 APC-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016), premium grade
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G4S linker分子别名

G4S linker

G4S linker分子背景

The poly-Glycine-Serine (G4S) linker is a type of flexible, unstructured synthetic peptide linker sequence often leveraged to connect the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The linker itself consists of a core pentapeptide sequence, Gly-Gly-Gly-Gly-Ser, that is repeated and commonly found as either a 15-mer (G4S)3 or20-mer(G4S) 4 within scFv-based CARs and scFv fragments. The linker sequence length plays a role in controlling scFv stability and the noncovalent association between the VH and VL domains.

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