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GPR75信息

英文名称:Probable G-protein coupled receptor 75
中文名称:G蛋白偶联受体-75
靶点别称
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

GPR75产品列表

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GPR75分子别名

GPRchr2, WI31133

GPR75分子背景

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

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