Chimeric HLA-A*0201 (H-2Kb α3) & B2M & GP100(YLEPGPVTA) 靶点蛋白|抗体药物|临床药物信息 - ACROBiosystems中国

> 【Chimeric HLA-A*0201 (H-2Kb α3) & B2M & GP100(YLEPGPVTA)】

Chimeric HLA-A*0201 (H-2Kb α3) & B2M & GP100(YLEPGPVTA)产品列表

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Protein (1)

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Biotin-labeled (1)

货号	物种	产品描述	蛋白结构	纯度	活性
HLG-H82E9	Human & Mouse	Biotinylated Chimeric HLA-A*02:01 (H-2Kb α3)&B2M&GP100 (YLEPGPVTA) Complex Protein (Monomer, MALS verified)

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Chimeric HLA-A*0201 (H-2Kb α3) & B2M & GP100(YLEPGPVTA)分子别名

Chimeric HLA-A*0201 (H-2Kb α3) & B2M & GP100(YLEPGPVTA)

Chimeric HLA-A*0201 (H-2Kb α3) & B2M & GP100(YLEPGPVTA)分子背景

Glycoprotein 100, is also well known as gp100 and Melanocyte protein PMEL. This antigen is a melanocyte-specific type I transmembrane glycoprotein and composed of 661 amino acids. Glycoprotein 100 is related to the tumor regression in metastatic melanoma patients after adoptive therapy, by which its epitopes being recognized by tumor lymphocytes and T-cells. The gp100280–288(YLEPGPVTA) was originally shown to be recognized by HLA-A*0201 tumor-infiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCR -T studies. The Human HLA-A*0201 Mouse H-2Kb gp100 (YLEPGPVTA) complex protein is a complex of HLA-A*0201 & H-2Kb of the MHC Class I, hB2M and YLEPGPVTA peptide of the gp100.

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