Postfusion glycoprotein F0/post-F protein (HMPV) 靶点蛋白|抗体药物|临床药物信息 - ACROBiosystems中国

> 【Postfusion glycoprotein F0/post-F protein (HMPV)】

Postfusion glycoprotein F0/post-F protein (HMPV)产品列表

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在线 (1)

物种

Human metapneumovirus (strain CAN97-83) (1)

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His Tag (1)

属性

Protein (1)

标记

Unconjugated (1)

货号	物种	产品描述	蛋白结构	纯度	活性
RSF-V52H5	Human metapneumovirus (strain CAN97-83)	Human metapneumovirus Post-fusion glycoprotein F0, His Tag (MALS verified)

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Postfusion glycoprotein F0/post-F protein (HMPV)分子别名

Postfusion glycoprotein F0/post-F protein (HMPV)

Postfusion glycoprotein F0/post-F protein (HMPV)分子背景

Human metapneumovirus (hMPV) is a paramyxovirHMPV G protein has not been shown to possess either hemagglutination or neuraminidase activity. Recombinant HMPV lacking the G protein replicates at levels similar to wild-type virus in vitro, but exhibits reduced titers in v ivo . One report suggested that HMPV G serves as an attachment protein and binds to cell surface glycosaminoglycans and thus may have a true attachment function us that is a common cause of bronchiolitis and pneumonia in children less than five years of age. The hMPV fusion (F) glycoprotein is the primary target of neutralizing antibodiesand is thus a critical vaccine antigen.

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