Frizzled-4 靶点蛋白|抗体药物|临床药物信息 - ACROBiosystems中国

> 【Frizzled-4】

Frizzled-4信息

英文名称：Frizzled-4
中文名称：卷曲蛋白-4
靶点别称：hFz4，FzE4，CD344，Frizzled 4， Seven Transmembrane Spanning Receptor，Fz-4，Frizzled Family Receptor 4，EVR1，Frizzled (Drosophila) Homolog 4，Frizzled Homolog 4 (Drosophila)，Exudative Vitreoretinopathy 1，WNT Receptor Frizzled-4，Frizzled Homolog 4，CD344 Antigen，FZD4S，FEVR，GPCR，Fz4

上市药物数量：0
临床药物数量：0
最高研发阶段：临床前

Frizzled-4产品列表

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在线 (1)

物种

Human (1)

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Fc Tag (1)

属性

Protein (1)

标记

Unconjugated (1)

货号	物种	产品描述	蛋白结构	纯度	活性
FZ4-H5250	Human	Human FZD4 /Frizzled-4 /CD344 Protein, with C-Fc Tag

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Frizzled-4 分子别名

FZD4,Frizzled-4,CD344,Fz-4,hFz4,FzE4

Frizzled-4 分子背景

Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).

Frizzled-4 前沿进展

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