Galectin-9 靶点蛋白|抗体药物|临床药物信息 - ACROBiosystems中国

> 【Galectin-9】

Galectin-9信息

英文名称：Galactoside-binding lectin Galectin 9
中文名称：半乳糖凝集素-9
靶点别称：Ecalectin，Tumor antigen HOM-HD-21，Galectin-9，Lectin， Galactoside-Binding， Soluble， 9，LGALS9

上市药物数量：0
临床药物数量：2
最高研发阶段：临床二期

Galectin-9分子别名

Galectin-9,LGALS9,Ecalectin

Galectin-9分子背景

Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.

Galectin-9临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验

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