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IL-1RL1信息

英文名称:Interleukin-1 receptor-like 1
中文名称:白介素1受体样蛋白1
靶点别称:ST2,IL1RL1,Protein ST2,DER4,T1,Interleukin 1 Receptor Like 1,Homolog Of Mouse Growth Stimulation-Expressed,Interleukin 1 Receptor-Related Protein,Growth Stimulation-Expressed,FIT-1,IL33R,ST2L,ST2V,Interleukin-1 Receptor-Like 1 Protein,EC:3.2.2.6,Interleukin-1 Receptor-Like 1
上市药物数量:0
临床药物数量:5
最高研发阶段:申请上市

IL-1RL1分子别名

IL1RL1,DER4,FIT-1,IL33R,ST2,ST2L,ST2V,T1

IL-1RL1分子背景

Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.

IL-1RL1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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