登录 | 注册    关注公众号  
微信公众号
搜索
 > 【MICA】

MICA信息

英文名称:MHC class I polypeptide-related sequence A
中文名称
靶点别称
上市药物数量:0
临床药物数量:3
最高研发阶段:临床一期

MICA分子别名

MIC-A

MICA分子背景

MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.

MICA临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

消息提示

请输入您的联系方式,再点击提交!

确定