Osteoactivin 靶点蛋白|抗体药物|临床药物信息 - ACROBiosystems中国

> 【Osteoactivin】

Osteoactivin信息

英文名称：Transmembrane glycoprotein NMB
中文名称：跨膜糖蛋白NMB
靶点别称：Transmembrane Glycoprotein，HGFIN，Transmembrane glycoprotein NMB，Hematopoietic growth factor inducible neurokinin-1 type，GPNMB，Glycoprotein Nmb，Hematopoietic Growth Factor Inducible Neurokinin-1，Glycoprotein Nonmetastatic Melanoma Protein B，Transmembrane Glycoprotein HGFIN，Glycoprotein (Transmembrane) Nmb，Glycoprotein Nmb-Like Protein，Osteoactivin，PLCA3，NMB，UNQ1725/PRO9925

上市药物数量：0
临床药物数量：1
最高研发阶段：临床二期

Osteoactivin产品列表

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产品库

在线 (1)

物种

Human (1)

标签

His Tag (1)

属性

Protein (1)

标记

Unconjugated (1)

货号	物种	产品描述	蛋白结构	纯度	活性
GPB-H5229	Human	Human Osteoactivin / GPNMB Protein, His Tag

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Osteoactivin分子别名

GPNMB,HGFIN,NMB,Osteoactivin

Osteoactivin分子背景

Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.

Osteoactivin临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验

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