英文名称:S100 Calcium Binding Protein P 中文名称:S100P 靶点别称:Migration-Inducing Gene 9 Protein,S100 Calcium-Binding Protein P,Protein S100-P,Protein S100-E,MIG9,S100E
上市药物数量:0 临床药物数量:0 最高研发阶段:临床前
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S100P 分子别名
S100P,S100E,MIG9
S100P 分子背景
S100 calcium-binding protein P (S100P),a member of the S-100 family, is also known as protein S100-P, migration-inducing gene 9 protein (MIG9) and protein S100-E,which contains two EF-hand domains. As for subunit structure,S100P is homodimer and heterodimer with S100A1. S100P may function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, S100P functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. Furthermore,S100P may stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).