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 > 【Serpin E2】

Serpin E2信息

英文名称:Sodium channel protein type IX alpha subunit
中文名称:IX型钠通道蛋白α亚基
靶点别称:Voltage-Gated Sodium Channel Subunit Alpha Nav1.7,HNE-Na,PN1,Sodium Channel, Voltage Gated, Type IX Alpha Subunit,Neuroendocrine sodium channel,Sodium channel protein type IX subunit alpha,Peripheral sodium channel 1,Sodium channel protein type 9 subunit alpha,GEFSP7,HSAN2D,Nav1.7,FEB3B,NE-NA,ETHA,SFNP,NAV1.7 Voltage-Gated Sodium Channel,NENA,SCN9A,Sodium Voltage-Gated Channel Alpha Subunit 9,Sodium Channel, Voltage-Gated, Type IX, Alpha Polypeptide,Sodium Channel, Voltage-Gated, Type IX, Alpha
上市药物数量:1
临床药物数量:10
最高研发阶段:批准上市

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Serpin E2 分子别名

SERPINE2,Glia-derived nexin,GDN,Peptidase inhibitor 7,PI-7,Protease nexin 1,PN-1,Serpin E2,SerpinE2,PI7

Serpin E2 分子背景

SERPINE2 is also known as Glia-derived nexin (GDN), Peptidase inhibitor 7 (PI7), Protease nexin 1(PN1). SERPINE2 is a secreted glycoprotein which belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). PAI-1 / GDN is also implicated in adipose tissue development. It suggests that PAI-1 inhibitors serve in the control of atherothrombosis. Defects in Serpin E1 / PN1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SerpinE1 defect in the plasma.

Serpin E2 前沿进展

Serpin E2上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

Serpin E2临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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