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 > 【TNF-beta】

TNF-beta信息

英文名称：Tumor necrosis factor β
中文名称：肿瘤坏死因子β
靶点别称：TNF Superfamily Member 1，TNLG1E，LT，Lymphotoxin-alpha，TNFSF1，Tumor Necrosis Factor Ligand Superfamily Member 1，Tumor Necrosis Factor Beta，LT-alpha，LTA#TNFB，LTA，Lymphotoxin Alpha，TNF-Beta，TNFB，Lymphotoxin Alpha (TNF Superfamily， Member 1)，Tumor Necrosis Factor Ligand 1E，Truncated Lymphotoxin Alpha，TNF Superfamily， Member 1
上市药物数量：15
临床药物数量：3
最高研发阶段：批准上市

TNF-beta产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
TNB-H5263
Human		 Human TNF-beta / Lymphotoxin-alpha Protein, Fc Tag (MALS verified)
TNB-H52H3
Human		 Human TNF-beta / Lymphotoxin-alpha Protein, His Tag (MALS verified)
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TNF-beta分子别名

LTA,DAMA-25N12,13-004,LT,TNFB,TNFSF1,LT-alpha,TNF-beta

TNF-beta分子背景

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

TNF-beta上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

TNF-beta临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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