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LRRC32信息

英文名称:Transforming growth factor beta activator LRRC32
中文名称:糖蛋白A主导重复序列
靶点别称:Leucine Rich Repeat Containing 32,D11S833E,Garpin,Leucine-Rich Repeat-Containing Protein 32,LRRC32,Transforming Growth Factor Beta Activator LRRC32,GARP,Glycoprotein A Repetitions Predominant
上市药物数量:0
临床药物数量:5
最高研发阶段:临床一期

LRRC32产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
LR2-H5256
Human
Human LRRC32 / GARP / Garpin Protein, Fc Tag
ACRO质量管理体系
 
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LRRC32分子别名

GARP,Garpin,D11S833E

LRRC32分子背景

Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naïve T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation.

LRRC32临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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