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 > 【B7-H5】

B7-H5信息

英文名称：V-domain Ig suppressor of T-cell activation
中文名称：T细胞活化的免疫球蛋白抑制V型结构域
靶点别称：Dies1，VSIR，V-Set Domain-Containing Immunoregulatory Receptor，DD1alpha，B7-H5，PD-1H，B7H5，GI24，Stress-induced secreted protein-1，PP2135，SISP1，UNQ730/PRO1412，V-type immunoglobulin domain-containing suppressor of T-cell activation，V-Set Immunoregulatory Receptor，V-Domain Ig Suppressor Of T Cell Activation，PDCD1 Homolog，C10orf54，Sisp-1，VISTA，Chromosome 10 Open Reading Frame 54，Stress Induced Secreted Protein 1，Platelet Receptor Gi24，Death Domain1alpha
上市药物数量：0
临床药物数量：6
最高研发阶段：临床二期

B7-H5产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
B75-H5259
Human		 Human B7-H5 / Gi24 / VISTA Protein, Fc Tag
B75-H5258
Human		 Human B7-H5 / Gi24 / VISTA Protein, Mouse IgG2a Fc Tag, low endotoxin
B75-H82E1
Human		 Biotinylated Human B7-H5 / Gi24 / VISTA Protein, Avitag,His Tag
B75-C5220
Rhesus macaque		 Rhesus macaque B7-H5 / Gi24 / VISTA Protein, His Tag
B75-H52H0
Human		 Human B7-H5 / Gi24 / VISTA Protein, His Tag (MALS verified)
B75-H82F3
Human		 Biotinylated Human B7-H5 / Gi24 / VISTA Protein, Fc,Avitag™
B75-M52H7
Mouse		 Mouse B7-H5 / Gi24 / VISTA Protein, His Tag
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B7-H5分子别名

B7-H5,SISP1,Gi24,VISTA

B7-H5分子背景

Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

B7-H5临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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