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Nectin-4信息

英文名称:Nectin-4
中文名称:细胞黏附分子nectin-4
靶点别称:PRR4,LNIR,Nectin cell adhesion molecule 4,PVRL4,Ig superfamily receptor LNIR,Poliovirus receptor-related protein 4,NECTIN4,Poliovirus Receptor-Related 4,Nectin-4,Nectin 4,EDSS1
上市药物数量:1
临床药物数量:10
最高研发阶段:批准上市

Nectin-4产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
NE4-H52H3
Human
Human Nectin-4 Protein, His Tag (MALS verified)
NE4-H82E7
Human
Biotinylated Human Nectin-4 Protein, His,Avitag™ (MALS verified)
NE4-M52H3
Mouse
Mouse Nectin-4 Protein, His Tag (MALS verified)
CHEK-ATP035
Human
HEK293/Human Nectin-4 Stable Cell Line
MBS-K039
Human
Human Nectin-4-coupled Magnetic Beads
NE4-C5253
Cynomolgus
Cynomolgus Nectin-4 Protein, Fc Tag (MALS verified)
NE4-C52H4
Cynomolgus
Cynomolgus Nectin-4 Protein, His Tag (MALS verified)
NE4-C82E5
Cynomolgus
Biotinylated Cynomolgus Nectin-4 Protein, His,Avitag™ (MALS verified)
NE4-C82F6
Cynomolgus
Biotinylated Cynomolgus Nectin-4 Protein, Fc,Avitag™ (MALS verified)
NE4-H5255
Human
Human Nectin-4 Protein, Fc Tag (MALS verified)
NE4-H82E3
Human
Biotinylated Human Nectin-4 Protein, His,Avitag™ (MALS verified)
NE4-H82Ea
Human
Biotinylated Human Nectin-4 (32-153) Protein, His,Avitag™ (MALS verified)
NE4-H82Ec
Human
Biotinylated Human Nectin-4 (154-243) Protein, His,Avitag™
NE4-H82Ed
Human
Biotinylated Human Nectin-4 (244-349) Protein, His,Avitag™ (MALS verified)
NE4-H82F4
Human
Biotinylated Human Nectin-4 Protein, Fc,Avitag™ (MALS verified)
NE4-HF2H3
Human
FITC-Labeled Human Nectin-4 Protein, His Tag
NE4-M5257
Mouse
Mouse Nectin-4 Protein, Fc Tag (MALS verified)
NE4-M52Ha
Mouse
Mouse Nectin-4 Protein, His Tag, low endotoxin (MALS verified)
NE4-M82E7
Mouse
Biotinylated Mouse Nectin-4 Protein, His,Avitag™ (MALS verified)
NE4-M82F5
Mouse
Biotinylated Mouse Nectin-4 Protein, Fc,Avitag™ (MALS verified)
NE4-R5255
Rat
Rat Nectin-4 Protein, Fc Tag (MALS verified)
ACRO质量管理体系
 
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Nectin-4分子别名

NECTIN4,LNIR, PRR4, PVRL4

Nectin-4分子背景

Nectin-4(Nectin cell adhesion molecule 4) is a Nectin and nectin-like family of cell adhesion molecules. It is found in high levels in normal embryonic and fetal tissues, but decreases after adulthood and is limited in distribution in healthy tissues. Nectin-4 is overexpressed in a variety of tumor cells and promotes tumor cell growth and proliferation. Solid tumors with high expression of Nectin-4 include bladder cancer, pancreatic cancer, triple negative breast cancer, non-small cell lung cancer, stomach cancer, esophageal cancer, ovarian cancer and many other cancers. Studies have found that Nectin-4 promotes tumor cell proliferation, differentiation, migration and invasion by activating the PI3K/Akt pathway, and is believed to play an important role in the occurrence and metastasis of cancer. It is based on these research backgrounds that drug research targeting this target has emerged.

Nectin-4上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

Nectin-4临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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