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IgG2 Fc产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
IG2-H5206
Human
Human IgG2 Fc Protein, Tag Free (MALS & SPR verified)
ACRO质量管理体系
 
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IgG2 Fc分子别名

IGHG2

IgG2 Fc分子背景

Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).

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