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 > 【GM-CSF R alpha】

GM-CSF R alpha信息

英文名称：Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
中文名称：粒细胞-巨噬细胞集落刺激因子受体α亚基
靶点别称：GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
上市药物数量：0
临床药物数量：4
最高研发阶段：临床三期

GM-CSF R alpha产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
GRA-H52H7
Human		 Human GM-CSF R alpha Protein, His Tag (SPR verified)
GMA-M52H3
Mouse		 Mouse GM-CSF R alpha Protein, His Tag
GRA-H5255
Human		 Human GM-CSF R alpha Protein, Fc Tag
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GM-CSF R alpha分子别名

GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116

GM-CSF R alpha分子背景

GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

GM-CSF R alpha临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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