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 > 【Klotho beta】

Klotho beta信息

英文名称：Klotho beta
中文名称：Klotho β蛋白
靶点别称：Klotho Beta，Klotho Beta-Like Protein，B-Klotho，Klotho Beta Like，Beta-Klotho，EC 3.2.1，BKL，BetaKlotho，KLB
上市药物数量：0
临床药物数量：3
最高研发阶段：临床二期

Klotho beta产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
KLB-R52H8
Rhesus macaque		 Rhesus macaque Klotho beta / KLB Protein, His Tag
KLB-M52H7
Mouse		 Mouse Klotho beta / KLB Protein, His Tag
KLB-H52H4
Human		 Human Klotho beta / KLB Protein, His Tag
KLB-R52H6
Rat		 Rat Klotho beta / KLB Protein, His Tag
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Klotho beta分子别名

betaKlotho,beta-klotho,BKL,KLB,klotho beta like,klotho beta-like protein

Klotho beta分子背景

KLB (Klotho Beta) is a Protein Coding gene. Among its related pathways are RET signaling and HIV Life Cycle. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL. Klotho Beta is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of βKlotho was down-regulated in human hepatocellular carcinoma tissues compared with that in paired adjacent non-tumourous liver tissues. Hepatoma cells also showed decreased expression of βKlotho compared with normal hepatocyte cells. Reintroduction of βKlotho into hepatoma cells inhibited their proliferation.

Klotho beta临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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